Gentamicin Induces Renal Morphopathology in Wistar Rats
نویسندگان
چکیده
منابع مشابه
ameliorative effects of metformin on renal histologic and biochemical alterations of gentamicin-induced renal toxicity in wistar rats
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BACKGROUND The aim of this study was to test the potential properties of metformin (MF) to protect the kidney from gentamicin (GM)-induced renal toxicity. MATERIALS AND METHODS In this preclinical study, 50 male Wistar rats were randomly divided into five groups of 10 rats in each. In the first group (group I), they were kept in the same condition as others without receiving drugs for 10 days...
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The effect of furosemide on gentamicin excretion and tissue accumulation was studied with clearance techniques in anesthetized rats, at two different infusion rates of saline or Ringer solution. Gentamicin (-20 mg/kg) was administered by constant intravenous infusion over a period of 3 h. With the low fluid infusion rate, furosemide (25 mg/kg intravenously) caused severe reduction in glomerular...
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ژورنال
عنوان ژورنال: International Journal of Morphology
سال: 2009
ISSN: 0717-9502
DOI: 10.4067/s0717-95022009000100011